Tirzepatide

$60.00

10 in stock

Dosage Information

  • Reconstitute: Add 2.0 mL bacteriostatic water → 10.0 mg/mL concentration.
  • Typical weekly range: 2.5–15 mg once weekly (gradual 4‑week titration steps).
  • Easy measuring: At 10.0 mg/mL, 1 unit = 0.01 mL = 100 mcg on a U‑100 insulin syringe.
  • Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); use within 28 days.
Week Daily Dose (mcg) Units (per injection) (mL)
Weeks 1–4 2.5 mg 12.5 units (0.125 mL)
Weeks 5–8 5 mg 25 units (.25 mL)
Weeks 9–12 7.5 mg 37.5 units (.375 mL)
Weeks 13–16 10 mg 50 units (.5 mL)

Product Description:

Tirzepatide (brand names Mounjaro for type 2 diabetes and Zepbound for weight management) is a synthetic 39-amino-acid peptide that acts as a dual receptor agonist for GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). It features a C20 fatty diacid modification that binds to albumin, extending its half-life for once-weekly subcutaneous injection.

How It Works

Tirzepatide mimics the actions of two natural gut hormones:

  • GLP-1 receptor activation: Slows gastric emptying, increases satiety (feeling of fullness), suppresses appetite via brain signaling, stimulates glucose-dependent insulin release, and reduces glucagon secretion.
  • GIP receptor activation: Enhances insulin secretion, improves insulin sensitivity, and supports fat metabolism. The dual action creates synergy beyond what GLP-1 agonists alone (like semaglutide) achieve.

Overall effects include:

  • Better blood sugar control
  • Significant appetite reduction and lower calorie intake
  • Increased energy expenditure and fat breakdown (especially visceral fat)
  • Improved metabolic health markers

Approved Uses and Potential Benefits

Tirzepatide is FDA-approved for:

  • Improving glycemic control in adults and certain pediatric patients with type 2 diabetes (as an adjunct to diet and exercise).
  • Chronic weight management in adults with obesity (BMI ≥30) or overweight (BMI ≥27) with at least one weight-related condition (e.g., hypertension, dyslipidemia, or type 2 diabetes).

Clinical trials (SURPASS and SURMOUNT series) have shown:

  • Substantial weight loss: Average 15–21% body weight reduction at higher doses (10–15 mg) over 72 weeks, with many patients achieving 20%+ loss.
  • Excellent HbA1c reductions (often >2%).
  • Improvements in cardiovascular risk factors, lipid profiles, blood pressure, and liver fat.
  • Better overall body composition and quality of life.

In fitness, bodybuilding, and wellness communities, it is popular for fat loss, body recomposition, and metabolic optimization.

Important Caveats

  • Side effects: Mostly gastrointestinal (nausea, vomiting, diarrhea, constipation) especially during dose escalation. Other possible effects include injection-site reactions, fatigue, or gallbladder issues. It carries a boxed warning for potential risk of thyroid C-cell tumors (seen in rodents).
  • Not suitable for everyone: Contraindicated in people with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2. Requires medical supervision.
  • Regulatory note: While the pharmaceutical versions are FDA-approved, research/gray-market or compounded versions vary in quality and purity. It is banned by WADA for athletes.

Bottom line: Tirzepatide is a highly effective dual-agonist peptide that delivers superior weight loss and metabolic benefits compared to earlier GLP-1 options, thanks to its innovative GIP + GLP-1 action. It fits well in your EDB LLC peptide lineup alongside products like Semaglutide, Retatrutide, Tesamorelin, etc. For product descriptions, emphasize its research/therapeutic context, high-purity sourcing, strong legal disclaimers, and the absolute need to consult a qualified healthcare professional. Always pair with diet and exercise for best results.

 

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