TB-500
$51.00
10 in stock
Dosage Information
- Reconstitute: Add 3.0 mL bacteriostatic water → ~3.33 mg/mL concentration.
- Typical daily range: 500–1000 mcg once daily (gradual titration recommended).
- Easy measuring: At 3.33 mg/mL, 1 unit = 0.01 mL ≈ 33.3 mcg on a U‑100 insulin syringe.
- Storage: Lyophilized: store at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); do not freeze reconstituted solution.
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
| Weeks 1–2 | 500 mcg | 15 units (0.15 mL) |
| Weeks 3–4 | 600 mcg | 18 units (0.18 mL) |
| Weeks 5–8 | 750 mcg | 23 units (0.23 mL) |
| Weeks 9–12 | 1000 mcg | 30 units (0.30 mL) |
- Labs Attested
- COA Included
- For 21+ Only
- US Sourced
Product Description:
TB-500 (also known as Thymosin Beta-4 fragment or TB4 fragment) is a synthetic heptapeptide (sequence: Ac-LKKTETQ) consisting of 7 amino acids. It is a fragment of the naturally occurring 43-amino-acid protein Thymosin Beta-4 (Tβ4), which is found throughout the body (especially in platelets, wound fluid, and tissues involved in repair).
How It Works
TB-500 primarily works by mimicking key functions of Thymosin Beta-4, with its main mechanism centered on actin regulation:
- Actin sequestration and cell motility: It binds to G-actin (monomeric actin), helping regulate the polymerization/depolymerization of actin filaments. This promotes cell migration, shape changes, and movement of repair cells (like fibroblasts, keratinocytes, and stem cells) to sites of injury.
- Angiogenesis: Stimulates the formation of new blood vessels to improve nutrient/oxygen delivery to damaged tissues.
- Anti-inflammatory and anti-apoptotic effects: Reduces excessive inflammation, inhibits programmed cell death in stressed cells, and supports tissue remodeling with less scar formation.
- Tissue regeneration: Enhances collagen deposition, wound healing, and overall repair processes in muscles, tendons, ligaments, skin, and other tissues.
These effects make it more “systemic” in action compared to more localized peptides. Most evidence comes from preclinical (animal and in-vitro) studies on wound healing, muscle/tendon injuries, and inflammation models. Limited human data exists for the full Tβ4 protein (some small Phase 2 trials on topical use for wounds), but very little for the TB-500 fragment itself.
Potential Benefits and Why People Use It
In fitness, bodybuilding, regenerative medicine, and recovery communities, TB-500 is popular for:
- Accelerated injury recovery — especially soft tissue (muscles, tendons, ligaments), wounds, and post-surgery healing.
- Reduced inflammation and pain — helpful for chronic conditions, joint issues, or overuse injuries.
- Improved flexibility and mobility — by supporting tissue remodeling and reducing scar tissue.
- Systemic repair and endurance — potential benefits for overall recovery, cardiovascular health, and hair/skin regeneration in some studies.
It is often stacked with peptides like BPC-157 (BPC more localized/gut-focused; TB-500 more systemic/motility-focused), as they may complement each other for comprehensive healing.
Important Caveats
- Limited human evidence: Strong preclinical data, but robust, large-scale human clinical trials on TB-500 (the fragment) are lacking. Ongoing early-phase trials (e.g., for cardiovascular biomarkers) are exploring safety.
- Regulatory status: Not FDA-approved for any medical use. It is banned by WADA for athletes and sold as a research chemical. Quality/purity of products varies widely.
- Safety: Generally well-tolerated in animal studies with low toxicity reported, but human long-term safety data is minimal. Theoretical concerns include potential effects on cell migration in cancer contexts (though not strongly evidenced). Common anecdotal side effects are mild (e.g., injection-site reactions, fatigue, or headaches). Consult a healthcare professional before use.
Bottom line: TB-500 is a promising research peptide for tissue repair, flexibility, and recovery, driven by its role in actin dynamics and regeneration. It’s particularly appealing for athletes or those dealing with stubborn injuries. However, its use remains experimental due to limited human data and lack of regulatory approval. For your e-commerce peptide products (like at EDB LLC), emphasize high-quality sourcing, disclaimers, and the research-only context. Always prioritize professional medical advice.
You may also research
Related Compounds
BPC 157\TB-500
- Reconstitute: Add 3.0 mL bacteriostatic water → 3.33 mg/mL concentration.
- Typical daily range: 200–600 mcg once daily (gradual titration).
- Easy measuring: At 3.33 mg/mL, 1 unit = 0.01 mL ≈ 33.3 mcg on a U-100 insulin syringe.
- Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); avoid freeze–thaw cycles.
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
| Weeks 1–2 | 200 mcg (0.2 mg) | 6 units (0.06 mL) |
| Weeks 3–4 | 400 mcg (0.4 mg) | 12 units (0.12 mL) |
| Weeks 5–8+ | 600 mcg (0.6 mg) | 18 units (0.18 mL) |
BPC-157
BPC-157 is dosed at 200 mcg–600 mcg daily via subcutaneous injection in educational protocols. A 5 mg vial reconstituted with bacteriostatic water yields about 1.67 mg/mL. This information is for research and educational use only.
- Reconstitute: Add 3.0 mL bacteriostatic water → 1.67 mg/mL concentration.
- Typical daily range: 200–600 mcg once daily (gradual titration).
- Easy measuring: At 1.67 mg/mL, 1 unit = 0.01 mL ≈ 16.7 mcg on a U-100 insulin syringe.
- Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); avoid freeze–thaw cycles.
Route: Subcutaneous | Frequency: Once daily
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
| Weeks 1–2 | 200 mcg (0.2 mg) | 12 units (0.12 mL) |
| Weeks 3–4 | 400 mcg (0.4 mg) | 24 units (0.24 mL) |
| Weeks 5–8+ | 600 mcg (0.6 mg) | 36 units (0.36 mL) |
CJC-1295 no DAC\Ipamorelin
- Reconstitute: Add 3.0 mL bacteriostatic water → ~3.33 mg/mL total concentration (1.67 mg/mL each peptide).
- Typical daily range: 100–300 mcg of each peptide once daily (gradual titration).
- Easy measuring: At 3.33 mg/mL total, 1 unit = 0.01 mL ≈ 33.3 mcg of each peptide on a U-100 insulin syringe.
- Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); avoid freeze–thaw cycles.
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
| Weeks 1–2 | 100 mcg each | 3 units (0.03 mL) |
| Weeks 3–4 | 150 mcg each | 4.5 units (0.045 mL) |
| Weeks 5–6 | 200 mcg each | 6 units (0.06 mL) |
| Weeks 7–12 | 250–300 mcg each | 7.5–9 units (0.075–0.09 mL) |
GKC-CU 100MG
- Reconstitute: Add 3.0 mL bacteriostatic water → ~33.3 mg/mL concentration.
- Typical daily range: 1–2 mg once daily (gradual titration over 12 weeks).
- Easy measuring: At 33.3 mg/mL, 1 unit = 0.01 mL ≈ 333 mcg on a U-100 insulin syringe.
- Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); use within 30 days.
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
| Weeks 1–4 | 1.0 mg | 3 units (0.03 mL) |
| Weeks 5–8 | 1.5 mg | 4.5 units (0.045 mL) |
| Weeks 9–12 | 2.0 mg | 6 units (0.06 mL) |
GLOW
- Reconstitute: Add 3.0 mL bacteriostatic water → ~23.3 mg/mL concentration.
- Typical daily dose: 2,330 mcg (2.33 mg) once daily for 4 weeks.
- Easy measuring: At 33.3 mg/mL, 1 unit = 0.01 mL ≈ 333 mcg on a U-100 insulin syringe.
- Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); use within 4 weeks
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
| Weeks 1–4 | 2,330 mcg | 70.5 units (0.70 mL) |
IGF1-LR3
- Reconstitute: Add 3.0 mL bacteriostatic water → ~0.333 mg/mL concentration (333 mcg/mL).
- Typical daily range: 20–50 mcg once daily subcutaneously (gradual titration recommended).
- Easy measuring: At 0.333 mg/mL, 1 unit = 0.01 mL ≈ 3.33 mcg on a U-100 insulin syringe.
- Storage: Lyophilized: freeze at −20 °C (−4 °F) for up to 12 months; after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F) and use within 30 days; avoid repeated freeze–thaw cycles.
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
| Weeks 1–2 | 20 mcg (0.02 mg) | 6 units (0.06 mL) |
| Weeks 3–4 | 40 mcg (0.04 mg) | 12 units (0.12 mL) |
| Weeks 5–8 | 50 mcg (0.05 mg) | 15 units (0.15 mL) |
MOTS-c 20MG
- Reconstitute: Add 3.0 mL bacteriostatic water → ~6.67 mg/mL concentration.
- Typical daily range: 200–1,000 mcg once daily (gradual titration over 10 weeks).
- Easy measuring: At 6.67 mg/mL, 1 unit = 0.01 mL ≈ 66.7 mcg on a U‑100 insulin syringe.
- Storage: Lyophilized: freeze at −20 °C (−4 °F) or below; after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F) and use within 7 days for best potency.
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
| Weeks 1–2 | 200 mcg (0.2 mg) | 3 units (0.03 mL) |
| Weeks 3–4 | 400 mcg (0.4 mg) | 6 units (0.06 mL) |
| Weeks 5–6 | 600 mcg (0.6 mg) | 9 units (0.09 mL) |
| Weeks 7–8 | 800 mcg (0.8 mg) | 12 units (0.12 mL) |
| Weeks 9–10+ | 1,000 mcg (1.0 mg) | 15 units (0.15 mL) |
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
| Weeks 1–2 (Initial) | 600 mcg | 300 mcg BPC + 300 mcg TB-500 - 18 units (0.18 mL) |
| Weeks 3–4 (Loading) | 800 mcg | 400 mcg BPC + 400 mcg TB-500 - 24 units (0.24 mL |
| Weeks 5–8 (Maintenance) | 600 mcg | 300 mcg BPC + 300 mcg TB-500 - 18 units (0.18 mL) |
MOTS-C 40MG
- Reconstitute: Add 3.0 mL bacteriostatic water → ~13.33 mg/mL concentration.
- Typical daily range: 200–1,000 mcg once daily (gradual titration over 10 weeks).
- Easy measuring: At 13.33 mg/mL, 1 unit = 0.01 mL ≈ 133.3 mcg on a U‑100 insulin syringe.
- Storage: Lyophilized: freeze at −20 °C (−4 °F) or below; after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F) and use within 7 days for best potency.
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
| Weeks 1–2 | 200 mcg (0.2 mg) | 1.5 units (0.015 mL) |
| Weeks 3–4 | 400 mcg (0.4 mg) | 3 units (0.03 mL) |
| Weeks 5–6 | 600 mcg (0.6 mg) | 4.5 units (0.045 mL) |
| Weeks 7–8 | 800 mcg (0.8 mg) | 6 units (0.06 mL) |
| Weeks 9–10+ | 1,000 mcg (1.0 mg) | 7.5 units (0.075 mL) |
PT-141
- Reconstitute: Add 3.0 mL bacteriostatic water → ~3.33 mg/mL concentration.
- Typical daily range: 500–1500 mcg once daily (gradual titration over 16 weeks).
- Easy measuring: At 3.33 mg/mL, 1 unit = 0.01 mL ≈ 33.3 mcg on a U-100 insulin syringe.
- Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); avoid freeze–thaw cycles.
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
| Weeks 1–8 | 500 mcg (0.5 mg) | 15 units (0.15 mL) |
| Weeks 9–12 | 1000 mcg (1.0 mg) | 30 units (0.30 mL) |
| Weeks 13–16 | 1500 mcg (1.5 mg) | 45 units (0.45 mL) |
Retatrutide 20MG
- Reconstitute: Add 2.0 mL bacteriostatic water → ~10.0 mg/mL concentration.
- Typical weekly range: 2–8 mg once weekly (gradual escalation over 8–12 weeks).
- Easy measuring: At 10.0 mg/mL, 1 unit = 0.01 mL ≈ 100 mcg on a U-100 insulin syringe.
- Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F) for up to 4 weeks.
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
| Weeks 1–4 | 2 mg (2000 mcg) | 20 units (0.20 mL) |
| Weeks 5–8 | 4 mg (4000 mcg) | 40 units (0.40 mL) |
| Weeks 9–12 | 6 mg (6000 mcg) | 60 units (0.60 mL) |
| Weeks 13+ | 8 mg (8000 mcg) | 80 units (0.80 mL) |
Retatrutide 40MG
- Reconstitute: Add 2.0 mL bacteriostatic water → ~20.0 mg/mL concentration.
- Typical weekly range: 2–8 mg once weekly (gradual escalation over 8–12 weeks).
- Easy measuring: At 20.0 mg/mL, 1 unit = 0.01 mL ≈ 200 mcg on a U-100 insulin syringe.
Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F) for up to 4 weeks
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
| Weeks 1–4 | 2 mg (2000 mcg) | 10 units (0.10 mL) |
| Weeks 5–8 | 4 mg (4000 mcg) | 20 units (0.20 mL) |
| Weeks 9–12 | 6 mg (6000 mcg) | 30 units (0.30 mL) |
| Weeks 13+ | 8 mg (8000 mcg) | 40 units (0.40 mL) |
